Which substance can cause tactile hallucinations?

Cocaine is known to cause tactile hallucinations, particularly in cases of overdose or chronic use. These hallucinations often manifest as sensations of insects crawling on or under the skin, which is commonly referred to as formication. This effect is related to the way cocaine interacts with the central nervous system, leading to heightened sensory perception and altered states of awareness.

Caffeine does not typically cause tactile hallucinations; instead, it can lead to increased alertness and anxiety when consumed in large amounts. CEA, likely referring to a type of illicit substance, varies in effects but is not widely recognized for inducing tactile hallucinations. Ergot, while it can cause hallucinations due to its alkaloids, primarily affects visual perception and has histories of causing vasoconstriction resulting in symptoms like gangrene rather than causing tactile sensations.

Thus, cocaine is the most well-documented substance associated with tactile hallucinations among the options presented.